The effect of ivermectin alone and in combination with cobicistat or elacridar in experimental Schistosoma mansoni infection in mice
Abstract Schistosoma mansoni is less susceptible to the antiparasitic drug ivermectin than other helminths.By inhibiting Phone Mount the P-glycoprotein or cytochrome P450 3A in mice host or parasites in a murine model, we aimed at increasing the sensitivity of S.mansoni to the drug and thus preventing infection.We assigned 124 BALB/c mice to no tre